Position Description

The position will be in translational science team. The candidate will be leading a group of PhD investigators and be responsible for directing the scientific strategy of preclinical translational biology studies in Oncology or Immune Oncology (IO) to full fulfil the increasing needs as BeiGene research team is expanding our first-in-class and best-in-class portfolio in oncology and I/I. The successful candidate will be responsible for developing translational development strategies for BeiGene’s drugs, working with discovery team and clinical development team.

When working with discovery team, the candidate and team will deliver scientific mechanism data to help candidate selection for oncology and IO drug candidate. When working with clinical development/biomarker team, the candidate and team will deliver pharmacodynamics biomarker, combination strategy, predictive biomarker, and drug resistant mechanism to help our global clinical development.

Expertise in scientific understand of drug discovery, developing and qualifying biomarkers, and strong knowledge in immunology and tumor biology is required. The candidate will supervise laboratory-based experiments as well as work with contract research organizations and internal and external collaborators.

本职位属于转化科学团队。候选人将领导一组PhD研究人员，并负责指导肿瘤靶向或免疫肿瘤学 (IO)药物的临床前转化生物学研究的科学策略，以满足百济神州的研究团队扩大肿瘤学和 I/I的管线过程中的转化研究需求。成功的候选人将与发现团队和临床开发团队合作，负责制定百济神州药物的转化开发策略。

在与发现团队合作时，候选者和团队将提供科学的机制研究数据，以帮助候选药物选择。在与临床开发/生物标志物团队合作时，候选人和团队将带领药效学生物标志物、药物联用策略、预测性生物标志物和耐药机制等方面的研究，以推动我们创新药物的全球临床开发。

候选人需要对药物发现开发、生物标志物的鉴定有科学理解方面的专业知识，以及在免疫学和肿瘤生物学方面的深厚的知识。候选人将带领团队开展实验室的实验，并且也会与CRO和内部和外部合作者合作。

Skills/Knowledge Required:

• PhD in cell biology or immunology.

• At least 10 years of experience in biotech and pharmaceutical industry with good track record. Experience with Oncology and Immuno-Oncology programs is preferred.

• Demonstrate good scientific experience by good track record including peer-reviewed research publications

• Expertise in developing and implementing biomarker strategy, and strong knowledge in immunology and tumor biology

• Effective team building and teamwork skills and ability to interact with and manage research scientists, project teams, outside collaborators and commercial vendors

• Lead research teams with good skills to motivate, to organize and to drive for team productivity.

• Excellent communication and interpersonal skills demonstrated in a team environment

• 细胞生物学或免疫学博士。

• 至少10 年的生物技术和制药行业经验，并拥有良好的业绩记录。有肿瘤学和免疫肿瘤学项目经验者优先。

• 具有优秀的既往研究纪录（包括同行评审的研究出版物）以及良好的科学经验

• 具有开发和实施生物标志物策略的专业知识，以及在免疫学和肿瘤生物学方面的深厚知识

• 有效的团队建设和团队合作技能，以及与研究科学家、项目团队、外部合作者和供应商互动和管理的能力

• 领导具有良好技能的研究团队来激励、组织和推动团队生产力。

• 在团队环境中表现出出色的沟通和人际交往能力